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Tolfenamic acid, 99+%
NSAID that activates calcium-activated potassium channels | CAS: 13710-19-5 | C14H12ClNO2 | 261.705 g/mol
$167.18 - $255.97
Chemical Identifiers
| CAS | 13710-19-5 |
|---|---|
| Molecular Formula | C14H12ClNO2 |
| Molecular Weight (g/mol) | 261.705 |
| MDL Number | MFCD00133865 |
| InChI Key | YEZNLOUZAIOMLT-UHFFFAOYSA-N |
| Synonym | tolfenamic acid, clotam, n-3-chloro-2-methylphenyl anthranilic acid, 2-3-chloro-2-methylphenyl amino benzoic acid, tolfedine, acido tolfenamico, acide tolfenamique, acidum tolfenamicum, tolfine, n-2-methyl-3-chlorophenyl anthranilic acid |
| PubChem CID | 610479 |
| ChEBI | CHEBI:32243 |
| IUPAC Name | 2-(3-chloro-2-methylanilino)benzoic acid |
| SMILES | CC1=C(C=CC=C1Cl)NC2=CC=CC=C2C(=O)O |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAJ6125606
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Thermo Scientific Chemicals
J6125606 |
5 g |
Each for $167.18
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AAJ6125609
|
Thermo Scientific Chemicals
J6125609 |
10 g |
Each for $255.97
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Description
Tolfenamic acid is a non-steroidal anti-inflammatory agent. It interferes with synthesis of β-amyloid precursor protein, and thus Aβ peptides, by promoting degradation of an essential transcription factor. It inhibits fMLP- and A23187-induced Ca2+ influx in human PMNL with an IC50 value of approximately 20 μM.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
SolubilitySoluble in water (slightly), acetone (∼10 mg/ml), DMSO (52 mg/ml at 25°C), methanol (∼10 mg/ml) and ethanol (50 mg/ml).
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
Chemical Identifiers
| 13710-19-5 | |
| 261.705 | |
| YEZNLOUZAIOMLT-UHFFFAOYSA-N | |
| 610479 | |
| 2-(3-chloro-2-methylanilino)benzoic acid |
| C14H12ClNO2 | |
| MFCD00133865 | |
| tolfenamic acid, clotam, n-3-chloro-2-methylphenyl anthranilic acid, 2-3-chloro-2-methylphenyl amino benzoic acid, tolfedine, acido tolfenamico, acide tolfenamique, acidum tolfenamicum, tolfine, n-2-methyl-3-chlorophenyl anthranilic acid | |
| CHEBI:32243 | |
| CC1=C(C=CC=C1Cl)NC2=CC=CC=C2C(=O)O |
Specifications
| 13710-19-5 | |
| C14H12ClNO2 | |
| 5 g | |
| 14,9513 | |
| Soluble in water (slightly),acetone (∽10mg/ml),DMSO (52mg/ml at 25°C),methanol (∽10mg/ml) and ethanol (50mg/ml). | |
| CC1=C(C=CC=C1Cl)NC2=CC=CC=C2C(=O)O | |
| 261.705 | |
| CHEBI:32243 | |
| ≥99% | |
| Tolfenamic acid |
| White | |
| MFCD00133865 | |
| UN2811 | |
| tolfenamic acid, clotam, n-3-chloro-2-methylphenyl anthranilic acid, 2-3-chloro-2-methylphenyl amino benzoic acid, tolfedine, acido tolfenamico, acide tolfenamique, acidum tolfenamicum, tolfine, n-2-methyl-3-chlorophenyl anthranilic acid | |
| YEZNLOUZAIOMLT-UHFFFAOYSA-N | |
| 2-(3-chloro-2-methylanilino)benzoic acid | |
| 610479 | |
| 261.7 | |
| Crystalline Powder |
Safety and Handling
GHS H Statement
H301
Toxic if swallowed.
P264b-P270-P301+P310-P330-P501c
H301
DOTInformation : Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber : 237-264-3
RTECSNumber : CB2687500
TSCA : No
Recommended Storage : Ambient temperatures
RUO – Research Use Only