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Invitrogen™ Thyroglobulin Polyclonal Antibody
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Catalog No. PIPA582034
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100 μL
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Catalog No. Quantity
PIPA582034 100 μL
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Catalog No. PIPA582034 Supplier Invitrogen™ Supplier No. PA582034

Description

Rabbit Polyclonal Antibody

Immunogen sequence: KMCSADYADL LQTFQVFILD ELTARGFCQI QVKTFGTLVS IPVCNNSSVQ VGCLTRERLG VNVTWKSRLE DIPVASLPDL HDIERALVGK DLLGRFTDLI QSGSFQLHLD SKTFPAETIR FLQGDHFGTS PRTWFGCSEG FYQVLTSEAS QDGLGCVKCP EGS Highest antigen sequence indentity to the following orthologs: Mouse - 76%, Rat - 76%.

The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti-thyroglobulin autoantibodies were the first factor to be discovered. Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves diseases), with the highest level observed in Hashimoto thyroiditis. Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.

Specifications

Antigen Thyroglobulin
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TG
Gene Accession No. P01266
Gene Alias AITD3; cog; Colloid; congenital goiter; hereditary goitre; TG; Tgn; thyroglobulin; thyroglobulin precursor
Gene Symbols TG
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TG. Recombinant protein control fragment (Product #RP-100475).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7038
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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