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Thermo Scientific Chemicals Thiazolyl Blue tetrazolium bromide, 98%
CAS: 298-93-1 | C18H16BrN5S | 414.33 g/mol
$130.27 - $390.14
Chemical Identifiers
| CAS | 298-93-1 |
|---|---|
| Molecular Formula | C18H16BrN5S |
| Molecular Weight (g/mol) | 414.33 |
| MDL Number | MFCD00011964,MFCD00066662 |
| InChI Key | AZKSAVLVSZKNRD-UHFFFAOYSA-M |
| Synonym | thiazolyl blue, thiazolyl blue tetrazolium bromide, mmt tetrazolium, methylthiazoletetrazolium, mtt, thiazolyl blue monotetrazolium, thiazole blue, 3-4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide, mtt van, unii-euy85h477i |
| PubChem CID | 64965 |
| ChEBI | CHEBI:53233 |
| IUPAC Name | 2-(3,5-diphenyltetrazol-2-ium-2-yl)-4,5-dimethyl-1,3-thiazole;bromide |
| SMILES | [Br-].CC1=C(C)N=C(S1)[N+]1=NC(=NN1C1=CC=CC=C1)C1=CC=CC=C1 |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAL1193903
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Thermo Scientific Chemicals
L1193903 |
1 g |
Each for $130.27
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AAL1193906
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Thermo Scientific Chemicals
L1193906 |
5 g |
Each for $390.14
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Description
Used in measurement of cell proliferation. Produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.Thiazolyl Blue tetrazolium bromide is a dye used in measurement of cell proliferation. It is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. As an electron acceptor, it is utilized for studying nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsUsed in measurement of cell proliferation. Produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.Thiazolyl Blue tetrazolium bromide is a dye used in measurement of cell proliferation. It is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. As an electron acceptor, it is utilized for studying nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.
Solubility
Soluble in water, ethanol, 2-methoxyethanol and phosphate buffered saline.
Notes
Light, air and moisture sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.
Chemical Identifiers
| 298-93-1 | |
| 414.33 | |
| AZKSAVLVSZKNRD-UHFFFAOYSA-M | |
| 64965 | |
| 2-(3,5-diphenyltetrazol-2-ium-2-yl)-4,5-dimethyl-1,3-thiazole;bromide |
| C18H16BrN5S | |
| MFCD00011964,MFCD00066662 | |
| thiazolyl blue, thiazolyl blue tetrazolium bromide, mmt tetrazolium, methylthiazoletetrazolium, mtt, thiazolyl blue monotetrazolium, thiazole blue, 3-4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide, mtt van, unii-euy85h477i | |
| CHEBI:53233 | |
| [Br-].CC1=C(C)N=C(S1)[N+]1=NC(=NN1C1=CC=CC=C1)C1=CC=CC=C1 |
Specifications
| 298-93-1 | |
| Odorless | |
| MFCD00011964,MFCD00066662 | |
| 3825277 | |
| thiazolyl blue, thiazolyl blue tetrazolium bromide, mmt tetrazolium, methylthiazoletetrazolium, mtt, thiazolyl blue monotetrazolium, thiazole blue, 3-4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide, mtt van, unii-euy85h477i | |
| AZKSAVLVSZKNRD-UHFFFAOYSA-M | |
| 2-(3,5-diphenyltetrazol-2-ium-2-yl)-4,5-dimethyl-1,3-thiazole;bromide | |
| 64965 | |
| 414.33 | |
| Thiazolyl Blue tetrazolium bromide |
| ∽195°C (decomposition) | |
| C18H16BrN5S | |
| 1 g | |
| Air, light, and moisture sensitive | |
| Soluble in water,ethanol,2-methoxyethanol and phosphate buffered saline. | |
| [Br-].CC1=C(C)N=C(S1)[N+]1=NC(=NN1C1=CC=CC=C1)C1=CC=CC=C1 | |
| 414.33 | |
| CHEBI:53233 | |
| 98% |
Safety and Handling
GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P201-P202-P261-P264b-P271-P280i-P281-P302+P352-P304+P340-P305+P351+P338-P308+P313-P332+P313-P362-P501c
H315-H319-H335-H341
EINECSNumber : 206-069-5
RTECSNumber : XF8060000
TSCA : Yes
Recommended Storage : Ambient temperatures; Store under Nitrogen
RUO – Research Use Only