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Invitrogen™ TGF alpha Recombinant Mouse Monoclonal Antibody (tAb2)
Mouse Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA551826
Description
tAb2 binds the N-terminal sequence of transforming growth factor alpha, VVSHFND (with residues 4 to 7 being the minimal binding epitope).
TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-alpha induces anchorage-independence transformation in cultured cells. Human, murine and rat TGF-alpha are cross-species reactive. TGFalpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.Specifications
| TGF alpha | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with 0.02% ProClin 300 | |
| P01135 | |
| TGFA | |
| Biologically active hemocyanin-coupled human TGFalpha (N-terminal). | |
| 200 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a κ |
| Dot Blot, ELISA | |
| tAb2 | |
| Unconjugated | |
| TGFA | |
| EGF-like TGF; ETGF; I79_019067; LOC100009150; Protransforming growth factor alpha; RATTGFAA; TFGA; TGF a; TGF type 1; TGF α; TGFA; TGFAA; TGFalpha; TGF-alpha; TGFα; Transforming growth factor; Transforming growth factor alpha; transforming growth factor, alpha; transforming growth factor-alpha; wa1; wa-1; waved 1 | |
| Mouse | |
| Protein A | |
| RUO | |
| 7039 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |