Invitrogen™ TEAD1/2/3/4 Recombinant Rabbit Monoclonal Antibody (23GB4680)

TEAD1, TEAD2, TEAD3, and TEAD4 are members of the TEAD (TEA domain) family of transcription factors. These factors are known to play important roles in various biological processes, including development, cell proliferation, differentiation, and organogenesis. TEAD1, TEAD2, TEAD3, and TEAD4 exhibit overlapping but also distinct expression patterns and functions. They are involved in diverse cellular processes and have been implicated in the regulation of embryonic development, tissue homeostasis, cell fate determination, and tumor progression. TEAD proteins are known to interact with various co-factors, including the transcriptional co-activators YAP (Yes-associated protein) and TAZ (transcriptional co-activator with PDZ-binding motif), which play crucial roles in the Hippo signaling pathway. The interaction between TEAD and YAP/TAZ is essential for the activation of downstream target genes involved in cell proliferation and survival.