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Invitrogen™ TCL1A Polyclonal Antibody
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Catalog No. PIPA517633
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100 μL
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Catalog No. Quantity
PIPA517633 100 μL
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Catalog No. PIPA517633 Supplier Invitrogen™ Supplier No. PA517633
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Description

Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody.

Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha or TCR-beta regulatory elements (summarized by Virgilio et al., 1998). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (Laine et al., 2000).

Specifications

Antigen TCL1A
Applications Western Blot
Classification Polyclonal
Concentration 60 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 0.15M NaCl, 100 μg/mL BSA, 50% glycerol and no preservative, pH 7.5
Gene TCL1A
Gene Accession No. P56279
Gene Alias oncogene TCL1; Oncogene TCL-1; Protein p14 TCL1; T cell lymphoma breakpoint 1; T-cell leukemia/lymphoma 1A; T-cell leukemia/lymphoma protein 1A; T-cell leukemia/lymphoma protein 1A (P14 TCL1 protein) (TCL1 oncogene) (TCL-1 protein); T-cell lymphoma breakpoint 1; T-cell lymphoma-1; T-cell lymphoma-1A; TCL1; TCL-1; TCL1A
Gene Symbols TCL1A
Host Species Rabbit
Immunogen Synthetic peptide corresponding to the amino-terminal sequence of human TCL1.
Purification Method Protein A, Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8115
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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