missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. Diphenylmethanes
  8. Tamoxifen, 98%

Tamoxifen, 98%

Catalog No. AAJ63509ME
Change view
Click to view available options
Quantity:
500 mg
1 g
5 g
3 product options available for selection
Product selection table with 3 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
AAJ63509ME 500 mg
AAJ6350903 1 g
AAJ6350906 5 g
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 3 options available.
3 options
Catalog No. AAJ63509ME Supplier Thermo Scientific Chemicals Supplier No. J63509ME
Only null left

Description

Tamoxifen (citofen, CAS # 10540-29-1) is an antineoplastic agent that has its effect through the estrogen receptors. | CAS: 10540-29-1 | C26H29NO | 371.52 g/mol

Inhibitor of protein kinase C and induces apoptosis in cancer cells. It is utilized in the study on lipopolysaccharide (LPS)-induced microglial activation to know its effect.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Tamoxifen is a tertiary aminobenzene that acts by competitively binding and antagonizing estrogen receptors to reduce DNA synthesis
  • When estradiol cannot bind estrogen receptors, the DNA response element is not activated
  • Tamoxifen upregulates the production of TGFb and slows tumor growth
  • Tamoxifen inhibits the production of IGF-1, a stimulator of tumor growth

Application

  • Tamoxifen may be useful in the study of tumorigenesis, growth, and inflammation
  • It is suitable for in vitro experiments

Chemical Identifiers

CAS 10540-29-1
Molecular Formula C26H29NO
Molecular Weight (g/mol) 371.52
MDL Number MFCD00010454
InChI Key NKANXQFJJICGDU-QPLCGJKRSA-N
Synonym tamoxifen, trans-tamoxifen, crisafeno, soltamox, tamoxifene, diemon, tamoxifeno, tamoxifenum, citofen, istubol
PubChem CID 2733526
ChEBI CHEBI:41774
IUPAC Name (2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine
SMILES CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1

Specifications

Color White
Quantity 500 mg
Merck Index 14,9048
Solubility Information Insoluble in water; Soluble in methanol,ethanol,propanol or propylene glycol;Soluble in dimethyl sulfoxide,dichloromethane and ethanol; Insoluble in water.
Formula Weight 371.52
Percent Purity 98%
Physical Form Powder
Chemical Name or Material Tamoxifen

Safety and Handling

Hazard Category H302-H350-H360FD-H362
Hazard Statement GHS H Statement
H350-H360-H362
May cause cancer.
May damage fertility or the unborn child.
May cause harm to breast-fed children.
Precautionary Statement P201-P202-P260-P263-P264b-P270-P281-P301+P312-P308+P313-P330-P501c
EINECSNumber 234-118-0
RTECSNumber KR5919600
TSCA No
Recommended Storage Store at -20°C

RUO – Research Use Only