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Staurosporine, 99+%, Thermo Scientific Chemicals
Staurosporine (staurosporin, CAS # 62996-74-1) is a bacterial alkyloid isolated from Streptomyces staurosporeus.
$276.16 - $1261.27
Chemical Identifiers
| CAS | 62996-74-1 |
|---|---|
| Molecular Formula | C28H26N4O3 |
| Molecular Weight (g/mol) | 466.541 |
| MDL Number | MFCD00077402 |
| InChI Key | HKSZLNNOFSGOKW-ZYSRIHRCSA-N |
| Synonym | Antibiotic AM-2282 |
| PubChem CID | 49831000 |
| SMILES | CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
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AAJ62837MCR
|
Thermo Scientific Chemicals
J62837MCR |
1 mg |
Each for $276.16
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AAJ62837LB0
|
Thermo Scientific Chemicals
J62837LB0 |
5 mg |
Each for $710.79
|
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AAJ62837MA
|
Thermo Scientific Chemicals
J62837MA |
10 mg |
Each for $1,261.27
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Description
Broad spectrum protein kinase inhibitor Staurosporine is used as anti-fungal and anti-hypertensive, which results to study the anti-cancer treatment. It acts as a precursor to protein kinase inhibitor midostaurin. It is also used to induce cell death in Swiss Webster primary macrophage cells and to study the effect of caspase activation on human sperm quality.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Staurosporine is an indolocarbazole alkaloid capable of permeating cell membranes
- Staurosporine has anti-cancer properties that can induce apoptosis
- Staurosporine is a broad inhibitor of protein kinases, preventing growth and division cycles
Application
- Staurosporine is used for research on acute myeloid leukemia
- It is suitable for research applications including cell culture and biochemistry
Chemical Identifiers
| 62996-74-1 | |
| 466.541 | |
| HKSZLNNOFSGOKW-ZYSRIHRCSA-N | |
| 49831000 |
| C28H26N4O3 | |
| MFCD00077402 | |
| Antibiotic AM-2282 | |
| CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC |
Specifications
| Staurosporine | |
| 62996-74-1 | |
| C28H26N4O3 | |
| 1060573 | |
| Antibiotic AM-2282 | |
| HKSZLNNOFSGOKW-ZYSRIHRCSA-N | |
| 466.541 | |
| 466.54 | |
| Yellow | |
| Staurosporine |
| Powder | |
| 240°C to 243°C | |
| MFCD00077402 | |
| 14,8802 | |
| Soluble in DMSO or ethanol;Soluble in dimethyl sulfoxide ,dimethyl formamide,ethyl acetate,hot acetone and ethanol; Slightly soluble in chloroform and methanol; Insoluble in water. | |
| CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC | |
| 49831000 | |
| ≥99% | |
| 1 mg |
Safety and Handling
GHS H Statement
H350
May cause cancer.
P201-P202-P280-P308+P313-P501c
H351
RTECSNumber : KD5084000
TSCA : No
storageNote1 : -30° to -10°C
Recommended Storage : Store at -20°C
RUO – Research Use Only