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Invitrogen™ STAT6 Monoclonal Antibody (7D3)
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Catalog No. PIMA515659
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100 μL
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Catalog No. Quantity
PIMA515659 100 μL
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Catalog No. PIMA515659 Supplier Invitrogen™ Supplier No. MA515659
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Description

Mouse Monoclonal Antibody

MA5-15659 targets STAT6 in indirect ELISA, IF and WB applications and shows reactivity with Human, mouse, Non-human primate, and Rat samples. The MA5-15659 immunogen is purified recombinant fragment of human STAT6 expressed in E. Coli. MA5-15659 detects STAT6 which has a predicted molecular weight of approximately 94kDa.

STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation. STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.

Specifications

Antigen STAT6
Applications ChIP Assay, ELISA, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 7D3
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene STAT6
Gene Accession No. P42226, P52633
Gene Alias 12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
Gene Symbols STAT6
Host Species Mouse
Immunogen Purified recombinant fragment of human STAT6 expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20852, 362896, 6778
Target Species Human, Mouse, Rat, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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