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  6. Invitrogen™ STAT2 Monoclonal Antibody (K24015_11D7), Invitrogen™

Invitrogen™ STAT2 Monoclonal Antibody (K24015_11D7), Invitrogen™

Catalog No. MA556198
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200 μL
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MA556198 200 μL
MA555818 50 μL
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Catalog No. MA556198 Supplier Invitrogen™ Supplier No. MA556198
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Description

Mouse Monoclonal Antibody

Sequence of this protein is as follows: DEAFGCYYQE KVNLQERRKY LKHRLIVVSN RQVDELQQPL ELKPEPELES LELELGLVPE PELSLDLEPL LKAGLDLGPE LESVLESTLE PVIEPTLCMV

STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.

Specifications

Antigen STAT2
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone K24015_11D7
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Gene Stat2
Gene Accession No. P52630
Gene Alias 1110034C02Rik; 1600010G07Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; Aprf; AW109958; AW496480; DNA-binding protein APRF; EGK_03803; HIES; IMD44; interferon alpha induced transcriptional activator; ISGF-3; MGC59816; p113; signal transducer and activator of transcription 2; signal transducer and activator of transcription 2, 113kDa; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); STAT; STAT 2; STAT113; STAT2; STAT-2; Stat3
Gene Symbols Stat2
Host Species Mouse
Immunogen Recombinant human STAT2 (immunogen range is 671-770).
Purification Method Protein A
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6773
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b
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