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Invitrogen™ SR-BI/SR-BII Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA316805
Description
SR-BI/SR-BII Polyclonal Antibody for Western Blot, IHC (P), ICC/IF, Flow, IP
High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. SR-BI and SR-BII (previously known as SR-BI.2) are the alternatively spliced products of a single gene. SR-BII and SR-BI are identical except for the encoded c-terminal cytoplasmic domain. Both SR-BI and SR-BII bind HDL and mediates selective uptake of HDL cholesteryl ester, but with SR-BII having an approximately 4-fold lower efficiency than SR-BI. SR-BI and SR-BII are expressed primarily in liver and non-placental steroidgenic tissues. Although the role of these scavenger receptors is not completely clear, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with both isoforms mediating selective transfer of lipid between HDL and cells. Therefore, the relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells.Chemical Identifiers
| SR-BI/SR-BII | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human, Mouse, Rat | |
| SCARB2 | |
| 85 kDa lysosomal membrane sialoglycoprotein; 85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2; 9330185J12Rik; AI120173; AMRF; CD36; CD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor thrombospondin receptor)-like 1 (scavanger receptor class B type 1); CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II); CD36 antigen-like 1; CD36 antigen-like 2; CD36L1; CD36L2; Cla1; CLA-1; Collagen type I receptor, thrombospondin receptor-like 1; D5Ertd460e; EPM4; HDL QTL 1; Hdlq1; HDLQTL6; Hlb398; HLGP85; LGP85; LIMP II; LIMP2; LIMP-2; LIMPII; lysosome membrane protein 2; Lysosome membrane protein II; MLGP85; mSR-BI; Scarb1; Scarb2; scavanger receptor class B type 1; scavenger receptor b1; scavenger receptor class B member 1; Scavenger receptor class B member 2; scavenger receptor class B type I; scavenger receptor class B type III; scavenger receptor class B, member 1; scavenger receptor class B, member 2; scavenger receptor class B1; SRB1; SR-B1; SR-B1/B2; SRBI; SR-BI; SR-BI/BII; SR-BII | |
| SCARB1, SCARB2 | |
| Primary |
| Conc. Not Determined | |
| Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| Whole serum with 0.02% sodium azide | |
| O35114, P27615, P97943, Q14108, Q61009, Q8WTV0 | |
| 117106, 12492, 20778, 25073, 949, 950 | |
| A peptide from the extracellular domain (residues 230-380) of Scavenger Receptor-BI/BII that was expressed as two tandem copies in bacteria using the pET system. | |
| Antibody |
Specifications
| SR-BI/SR-BII | |
| Polyclonal | |
| Unconjugated | |
| SCARB2 | |
| 85 kDa lysosomal membrane sialoglycoprotein; 85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2; 9330185J12Rik; AI120173; AMRF; CD36; CD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor thrombospondin receptor)-like 1 (scavanger receptor class B type 1); CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II); CD36 antigen-like 1; CD36 antigen-like 2; CD36L1; CD36L2; Cla1; CLA-1; Collagen type I receptor, thrombospondin receptor-like 1; D5Ertd460e; EPM4; HDL QTL 1; Hdlq1; HDLQTL6; Hlb398; HLGP85; LGP85; LIMP II; LIMP2; LIMP-2; LIMPII; lysosome membrane protein 2; Lysosome membrane protein II; MLGP85; mSR-BI; Scarb1; Scarb2; scavanger receptor class B type 1; scavenger receptor b1; scavenger receptor class B member 1; Scavenger receptor class B member 2; scavenger receptor class B type I; scavenger receptor class B type III; scavenger receptor class B, member 1; scavenger receptor class B, member 2; scavenger receptor class B1; SRB1; SR-B1; SR-B1/B2; SRBI; SR-BI; SR-BI/BII; SR-BII | |
| Rabbit | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry | |
| Conc. Not Determined | |
| Whole serum with 0.02% sodium azide | |
| O35114, P27615, P97943, Q14108, Q61009, Q8WTV0 | |
| SCARB1, SCARB2 | |
| A peptide from the extracellular domain (residues 230-380) of Scavenger Receptor-BI/BII that was expressed as two tandem copies in bacteria using the pET system. | |
| RUO | |
| 117106, 12492, 20778, 25073, 949, 950 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |