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Invitrogen™ Sortilin Recombinant Rabbit Monoclonal Antibody (23GB4170)
Description
Sortilin Recombinant Monoclonal Antibody for Western Blot
Sortilin functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Sortilin is required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). It is also required for protein transport from the Golgi apparatus to the endosomes. Sortilin promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also, Sortilin acts as a receptor for neurotensin.
Specifications
Specifications
| Antigen | Sortilin |
| Applications | Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | 23GB4170 |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | Sort1 |
| Gene Accession No. | Q99523 |
| Gene Alias | 100 kDa NT receptor; 2900053A11Rik; AI852375; Glycoprotein 110; glycoprotein 95; Gp110; Gp95; LDLCQ6; mNTR3; neurotensin receptor 3; NT3; NTR3; Nts3; Ntsr3; Sort1; Sortilin; sortilin 1 |
| Gene Symbols | Sort1 |
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