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Invitrogen™ Sortilin Recombinant Rabbit Monoclonal Antibody (23GB4170)

Catalog No. MA553703
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100 μL
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MA553703 20 μL
MA553702 100 μL
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Catalog No. MA553703 Supplier Invitrogen™ Supplier No. MA553703
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Rabbit Recombinant Monoclonal Antibody

Sortilin Recombinant Monoclonal Antibody for Western Blot

Sortilin functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Sortilin is required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). It is also required for protein transport from the Golgi apparatus to the endosomes. Sortilin promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also, Sortilin acts as a receptor for neurotensin.

Specifications

Antigen Sortilin
Applications Western Blot
Classification Recombinant Monoclonal
Clone 23GB4170
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Sort1
Gene Accession No. Q99523
Gene Alias 100 kDa NT receptor; 2900053A11Rik; AI852375; Glycoprotein 110; glycoprotein 95; Gp110; Gp95; LDLCQ6; mNTR3; neurotensin receptor 3; NT3; NTR3; Nts3; Ntsr3; Sort1; Sortilin; sortilin 1
Gene Symbols Sort1
Host Species Rabbit
Immunogen A synthesized peptide derived from Sortilin (650-770AA).
Purification Method Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6272
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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