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Invitrogen™ SNTG2 Polyclonal Antibody

Description
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: ILRFYTAQDG TDWLRAVSAN IRELTLQNMK MANKCCSPSD QVVHMGWVNE KLQGADSSQT FRPKFLALK Highest antigen sequence indentity to the following orthologs: Rat - 76%, Mouse - 77%.
Syntrophin gamma 2 encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described.
Specifications
Specifications
| Antigen | SNTG2 |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Concentration | 0.4 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | SNTG2 |
| Gene Accession No. | Q9NY99 |
| Gene Alias | 2210008K22Rik; 9530013L23; BB121248; G2SYN; Gamma-2-syntrophin; gamma2-syntrophin; MGC133174; SNTG2; SYN5; syntrophin; syntrophin 5; syntrophin gamma 2; syntrophin, gamma 2; syntrophin-5 |
| Gene Symbols | SNTG2 |
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