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Invitrogen™ Smallpox Virus B5R Monoclonal Antibody (1J2F3)
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Catalog No. 01676594
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100 μg
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01676594 100 μg
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Catalog No. 01676594 Supplier Invitrogen™ Supplier No. MA141212

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Mouse Monoclonal Antibody

This antibody is predicted to react with Bovinepox virus, Ectromelia virus, Monkeypox virus, Rabbitpox virus, and vaccinia virus. Immunogen sequence: IQEYNLIRTY KKVDK.

B5R is an EEV-specific Type I membrane glycoprotein essential for EEV formation. Vaccinia virus, a member of Poxviridae family, is a dsDNA enveloped virus. It consists of 4 types of virion stages among which extracellular enveloped virus (EEV) is critical for cell-to-cell and long range viral infection. Some cellular antigens are associated with EEV and these vary with the cell type used to grow the virus. B5R consists of a large ectodomain containing regions similar to SCR domains of complement regulatory proteins followed by a transmembrane region and a cytoplasmic tail. B5R is essential for efficient wrapping of IMV, actin tail formation, normal plaque size, virus virulence, and for EEV formation.

Specifications

Antigen Smallpox Virus B5R
Applications Western Blot
Classification Monoclonal
Clone 1J2F3
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Host Species Mouse
Immunogen Amino acids 33-47 of the B5R protein.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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