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Invitrogen™ SHBG Polyclonal Antibody

Description
Immunogen sequence: LRPVLPTQSA HDPPAVHLSN GPGQEPIAVM TFDLTKITKT SSSFEVRTWD PEGVIFYGDT NPKDDWFMLG LRDGRPEIQL HNHWAQLTVG AGPRLDDGRW HQVEVKMEGD SVLLEVDGEE VLRLRQVSGP LTSKRHPIMR I; Positive Samples: A-549, Human placenta, Mouse testis.
SHBG is a steroid binding protein that was first described as a plasma protein secreted by the liver and is thought to participate in the regulation of steroid responses. SHBG transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Low plasma SHBG levels are associated with obesity, abdominal adiposity, metabolic syndrome, and predict the development of type 2 diabetes. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus.
Specifications
Specifications
| Antigen | SHBG |
| Applications | ELISA, Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.73 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | SHBG |
| Gene Accession No. | P04278, P08689, P97497 |
| Gene Alias | ABP; Abpa; androgen binding protein; Androgen binding protein (ABP); SBP; sex hormone binding globulin; Sex hormone binding globulin or androgen-binding protein (other gene product from ABP gene); sex hormone-binding globulin; Sex hormone-binding globulin (SHBG); Sex steroid binding protein (SBP); Sex steroid-binding protein; Shbg; TeBG; testis-specific androgen-binding protein; Testosterone binding beta globulin; testosterone-binding beta-globulin; testosterone-estradiol-binding globulin; Testosterone-Estradiol-Binding Globulin (TEBG); Testosterone-estrogen-binding globulin |
| Gene Symbols | SHBG |
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