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Invitrogen™ SAP18 Monoclonal Antibody (3B2)
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Catalog No. PIMA524433
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100 μg
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Catalog No. Quantity
PIMA524433 100 μg
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Catalog No. PIMA524433 Supplier Invitrogen™ Supplier No. MA524433
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Description

Mouse Monoclonal Antibody

Peptide Sequence: MAVESRVTQE EIKKEPEKPI DREKTCPLLL RVFTTNNGRH HRMDEFSRGN VPSSELQIYT WMDATLKELT SLVKEVYPEA RKKGTHFNFA IVFTDVKRPG YRVKEIGSTM SGRKGTDDSM TLQSQKFQIG DYLDIAITPP NRAPPTSGRM RPY.

SAP18 is involved in histone acetylation, which plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.

Specifications

Antigen SAP18
Applications ELISA, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 3B2
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene SAP18
Gene Accession No. O00422
Gene Alias 18 kDa Sin3-associated polypeptide; 2HOR0202; C530046K05Rik; cell growth inhibiting protein 38; cell growth-inhibiting gene 38 protein; cell growth-inhibiting protein 38; D11Ertd539e; EMegR4; GIG38; histone deacetlyase complex subunit SAP18; histone deacetylase complex subunit SAP18; SAP18; SAP18P; Sin3A associated protein 18; Sin3A associated protein 18kDa; Sin3A-associated protein, 18kDa; Sin3-associated polypeptide 18; sin3-associated polypeptide p18; sin3-associated polypeptide, 18 kDa; sin3-associated polypeptide, 18kDa; sin3-associated polypeptide, p18; Sinbp1
Gene Symbols SAP18
Host Species Mouse
Immunogen SAP18 (AAH30836, 1 a.a. ~ 153 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10284
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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