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Invitrogen™ RNF14 Polyclonal Antibody
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Catalog No. PIPA552594
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100 μL
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Catalog No. Quantity
PIPA552594 100 μL
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Catalog No. PIPA552594 Supplier Invitrogen™ Supplier No. PA552594
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GCTMGICSSC NFAFCTLCRL TYHGVSPCKV TAEKLMDLRN EYLQADEANK RLLDQRYGKR VIQKALEEME SKEWLEKNSK SCPCCGTPIE KLDGCNKMTC TGCMQYFCWI CMGSLSRANP YKHFNDPGSP CFNRLFYAVD VDDDIWEDEV Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 90%.

The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.

Specifications

Antigen RNF14
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene RNF14
Gene Accession No. Q9JI90, Q9UBS8
Gene Alias 2310075C09Rik; 2610005D23Rik; AA986456; androgen receptor associated protein 54; androgen receptor associated protein 54 (androgen receptor coactivator); androgen receptor-associated protein 54; ARA54; AU041447; D18Ertd188e; D7Bwg0165e; E3 ubiquitin-protein ligase RNF14; HFB30; HRIHFB2038; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF14; protein Triad2; RING finger protein 14; RNF14; TRIAD2; Triad2 protein; TRIAD2 type I
Gene Symbols RNF14
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RNF14. Recombinant protein control fragment (Product #RP-102289).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56736, 619577, 9604
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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