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Thermo Scientific Chemicals Rifampin, Molecular Biology Reagent
Rifampin (rifampicin), CAS # 13292-46-1, is a synthetic rifamycin antibiotic that works by inhibiting RNA and DNA synthesis and exhibits activity against the tuberculosis microbe. | CAS: 13292-46-1 | C43H58N4O12 | 822.953 g/mol
Supplier: Thermo Scientific Chemicals J6083606
Description
Antibiotic effective against mycobacteria. Can also inhibit DNA polymeraseRifampin is an antibiotic used in the treatment of tuberculosis and its related microbacterial infections. It is involved in the inhibition of DNA polymerase and RNA polymerase. As an antipruritic agent, it is used in the autoimmune cholestatic liver disease and primary biliary cirrhosis (PBC).
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Rifampin is a rifamycin class antibiotic synthesized to resemble the compound isolated from Amycolatopsis rifamycinica
Applications
- Rifampin can be used as a bacteriostatic that prevents RNA and DNA synthesis, particularly in mycobacteria
- It may also act as an antineoplastic, a neuroprotective, and inhibitor of angiogenesis
Specifications
| Rifampicin | |
| Powder | |
| 183°C to 188°C | |
| 5 g | |
| MFCD00151389 | |
| 14,8216 | |
| Soluble in DMSO or methanolSoluble in water,ethyl acetate,chloroform,methanol,tetrahydrofuran and dimethyl sulfoxide. | |
| CC1C=CC=C(C(=O)NC2=C(C3=C(C(=C4C(=C3C(=O)C2=CNN5CCN(CC5)C)C(=O)C(O4)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)C | |
| 131839595 | |
| Molecular Biology |
| Rifampin | |
| 13292-46-1 | |
| Brown/Red to Orange | |
| C43H58N4O12 | |
| 5723476 | |
| Rifampicin | |
| FZYOVNIOYYPUPY-HRJPTAQKSA-N | |
| 822.953 | |
| 822.94 |
Chemical Identifiers
| 13292-46-1 | |
| 822.953 | |
| FZYOVNIOYYPUPY-HRJPTAQKSA-N | |
| 131839595 |
| C43H58N4O12 | |
| MFCD00151389 | |
| Rifampicin | |
| CC1C=CC=C(C(=O)NC2=C(C3=C(C(=C4C(=C3C(=O)C2=CNN5CCN(CC5)C)C(=O)C(O4)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)C |
Safety and Handling
GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
H302-H315-H319-H335
EINECSNumber : 236-312-0
RTECSNumber : VJ7000000
TSCA : No
Recommended Storage : Store at -20°C
RUO – Research Use Only