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Invitrogen™ RFTN1 Polyclonal Antibody
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Catalog No. pipa583923
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100 μL
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PIPA583923 100 μL
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Catalog No. PIPA583923 Supplier Invitrogen™ Supplier No. PA583923
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ALHPFVQPTH EREKTPLEHI FRAILIKKTD RSQKTDLHNE GYILELDCCS SLDHPTDQKL IPEFIKKIQE AASQGLKFVG VIPQYHSSV Highest antigen sequence indentity to the following orthologs: Rat - 78%, Mouse - 78%.

Raftlin, also known as RFTN1 (raftlin, lipid raft linker 1), cell migration-inducing gene 2 protein, PIB10, PIG9 or MIG2, is a 578 amino acid cell membrane protein and lipid anchor that is essential for raft cell assembly and maintenance. A member of the raftlin family, Raftlin modulates B-cell antigen receptor-mediated signaling, TCR signals, and is involved in T cell-mediated immune responses. The gene encoding Raftlin maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Specifications

Antigen RFTN1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Rftn1
Gene Accession No. Q14699
Gene Alias 2310015n21rik; AI853526; Cell migration-inducing gene 2 protein; KIAA0084; MIG2; PIB10; PIG9; proliferation-inducing protein 10; proliferation-inducing protein 9; Raftlin; raftlin lipid raft linker 1; raftlin, lipid raft linker 1; raft-linking protein; Rftn1; RGD1310777; RGD1563347
Gene Symbols Rftn1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RFTN1. Recombinant protein control fragment (Product #RP-100953).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23180
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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