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Invitrogen™ RFFL Polyclonal Antibody

Description
Immunogen sequence: MKVKDLRDYL SLHDISTEMC REKEELVLLV LGQQPVISQE DRTRASTLSP DFPEQQAFLT QPHSSMVPPT SPNLPSSS Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 86%.
Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates.
Specifications
Specifications
| Antigen | RFFL |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | Rffl |
| Gene Accession No. | Q8WZ73 |
| Gene Alias | 1700051E09Rik; 4930516L10Rik; BG080975; CARP2; CARP-2; caspase regulator CARP2; Caspases-8 and -10-associated RING finger protein 2; E3 ubiquitin-protein ligase rififylin; Fring; FYVE-RING finger protein SAKURA; RFFL; RIFIFYLIN; ring finger and FYVE like domain containing E3 ubiquitin protein ligase; ring finger and FYVE like domain containing protein; ring finger and FYVE-like domain containing 1; ring finger and FYVE-like domain containing E3 ubiquitin protein ligase; RING finger and FYVE-like domain-containing protein 1; RING finger protein 189; RING finger protein 34-like; RING finger protein SAKURA; RING-type E3 ubiquitin transferase rififylin; RNF189; RNF34L |
| Gene Symbols | Rffl |
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