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Invitrogen™ RBM28 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA522103
Description
Recommended positive controls: 293T, A431, H1299, HepG2, Raji. Predicted reactivity: Mouse (80%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum (ER) membranes. Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, thus linking these intracellular compartments. The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface. With VAPA, may regulate ER morphology. Has a role in regulation of the actin cytoskeleton, cell polarity and cell adhesion. Binds to phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3. Also binds 25-hydroxycholesterol and cholesterol.Chemical Identifiers
| RBM28 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human | |
| Rbm28 | |
| 2810480G15Rik; AI503051; ANES; hypothetical protein MGC56258; RBM28; RNA binding motif protein 28; RNA-binding motif protein 28; RNA-binding protein 28; zgc:56258 | |
| Rbm28 | |
| Primary | |
| Antigen affinity chromatography |
| 1 mg/mL | |
| Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 | |
| Q9NW13 | |
| 55131 | |
| Recombinant protein encompassing a sequence within the C-terminus region of human RBM28. The exact sequence is proprietary. | |
| Antibody |
Specifications
| RBM28 | |
| Polyclonal | |
| Unconjugated | |
| Rbm28 | |
| 2810480G15Rik; AI503051; ANES; hypothetical protein MGC56258; RBM28; RNA binding motif protein 28; RNA-binding motif protein 28; RNA-binding protein 28; zgc:56258 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 55131 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 | |
| Q9NW13 | |
| Rbm28 | |
| Recombinant protein encompassing a sequence within the C-terminus region of human RBM28. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |