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Invitrogen™ RBM28 Polyclonal Antibody
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Catalog No. PIPA522103
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100 μL
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Catalog No. Quantity
PIPA522103 100 μL
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Catalog No. PIPA522103 Supplier Invitrogen™ Supplier No. PA522103
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, H1299, HepG2, Raji. Predicted reactivity: Mouse (80%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum (ER) membranes. Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, thus linking these intracellular compartments. The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface. With VAPA, may regulate ER morphology. Has a role in regulation of the actin cytoskeleton, cell polarity and cell adhesion. Binds to phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3. Also binds 25-hydroxycholesterol and cholesterol.

Specifications

Antigen RBM28
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Rbm28
Gene Accession No. Q9NW13
Gene Alias 2810480G15Rik; AI503051; ANES; hypothetical protein MGC56258; RBM28; RNA binding motif protein 28; RNA-binding motif protein 28; RNA-binding protein 28; zgc:56258
Gene Symbols Rbm28
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human RBM28. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55131
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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