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Invitrogen™ Rat IL-23 ELISA Kit
ELISA
Supplier: Invitrogen™ ERA28RB
Description
Rat IL-23 quantitates rat IL-23 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat IL-23.
IL-23 is a heterodimeric cytokine composed of the p40 subunit of IL-12 disulfide-linked with a protein p19. p19, like p35 of IL-12, is biologically inactive by itself. IL-23 interacts with IL-12Rbeta1 and an additional, novel beta2-like receptor subunit with STAT4 binding domain, termed IL-23R. IL-23 is secreted by activated mouse and human dendritic cells. Biological activities of mouse IL-23 are distinct from those of mouse IL-12. Mouse IL-23 was found not to induce significant amounts of IFN-γ. Mouse IL-23 does induce strong proliferation of memory T cells (but not naive T cells), whereas IL-12 has no effect on memory cells. Additionally, mouse IL-23 (but not IL-12) can activate mouse memory T cells to produce the proinflammatory cytokine IL-17. Human IL-23 has biological properties which are less distinct from human IL-12; human IL-23 induces proliferation of memory T cells and induces moderate levels of IFN-γ production by naive and memory T cells, as compared to IL-12.Chemical Identifiers
| il 23; IL 23 A; IL12B; Il-12 b; Il12p40; Il-12p40; il23; IL-23; IL-23 subunit alpha; Il23a; IL-23 A; IL-23-A; IL23P19; IL-23p19; ILN; Interleukin; interleukin 12 B; interleukin 23 p19 subunit; interleukin 23 subunit alpha; Interleukin 23, alpha subunit p19; interleukin-23 subunit alpha; Interleukin-23 subunit p19; interleukin-six, G-CSF related factor; JKA3 induced upon T-cell activation; MGC79388; P19; p40; RP23-388G23.1; SGRF; UNQ2498/PRO5798 | |
| 0.82 ng/mL | |
| ELISA | |
| Colorimetric Microplate Reader | |
| IL23A | |
| <10 | |
| HRP | |
| Plasma 50 μL, Serum 50 μL, Supernatant 50 μL | |
| IL-23 p19 | |
| 4 hrs 45 mins |
| 0.82 to 200 ng/mL | |
| HRP | |
| Plasma, Serum, Supernatant | |
| 155140 | |
| <12% | |
| Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
| RUO | |
| 2°C to 8°C | |
| 1 hrs 20 mins |
Specifications
| il 23; IL 23 A; IL12B; Il-12 b; Il12p40; Il-12p40; il23; IL-23; IL-23 subunit alpha; Il23a; IL-23 A; IL-23-A; IL23P19; IL-23p19; ILN; Interleukin; interleukin 12 B; interleukin 23 p19 subunit; interleukin 23 subunit alpha; Interleukin 23, alpha subunit p19; interleukin-23 subunit alpha; Interleukin-23 subunit p19; interleukin-six, G-CSF related factor; JKA3 induced upon T-cell activation; MGC79388; P19; p40; RP23-388G23.1; SGRF; UNQ2498/PRO5798 | |
| 0.82 ng/mL | |
| ELISA | |
| Colorimetric Microplate Reader | |
| IL23A | |
| <10 | |
| HRP | |
| RUO | |
| 2°C to 8°C | |
| 1 hrs 20 mins |
| 0.82 to 200 ng/mL | |
| HRP | |
| Plasma, Serum, Supernatant | |
| 155140 | |
| <12% | |
| Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
| 96 Tests | |
| Plasma 50 μL, Serum 50 μL, Supernatant 50 μL | |
| IL-23 p19 | |
| 4 hrs 45 mins |