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Invitrogen™ Rat IL-10 ELISA (For Lysates) Kit
ELISA
Supplier: Invitrogen™ ERA24RBX5
Description
Rat IL-10 quantitates rat IL-10 in cell lysate, tissue homogenate. The assay will exclusively recognize both natural and recombinant rat IL-10.
IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.Chemical Identifiers
| CSIF; cytokine; cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; Interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF | |
| 10 pg/mL | |
| ELISA | |
| Colorimetric Microplate Reader | |
| IL10 | |
| <10 | |
| HRP | |
| Cell Lysate 50 μL, Tissue Homogenate 50 μL | |
| IL-10 | |
| 4 hrs 45 mins |
| 10 to 6,000 pg/mL | |
| HRP | |
| Cell Lysates, Tissue Homogenates | |
| 25325 | |
| <12% | |
| Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
| RUO | |
| 2°C to 8°C | |
| 1 hrs 20 mins |
Specifications
| CSIF; cytokine; cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; Interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF | |
| 10 pg/mL | |
| ELISA | |
| Colorimetric Microplate Reader | |
| IL10 | |
| <10 | |
| HRP | |
| RUO | |
| 2°C to 8°C | |
| 1 hrs 20 mins |
| 10 to 6,000 pg/mL | |
| HRP | |
| Cell Lysates, Tissue Homogenates | |
| 25325 | |
| <12% | |
| Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
| 5 x 96 Tests | |
| Cell Lysate 50 μL, Tissue Homogenate 50 μL | |
| IL-10 | |
| 4 hrs 45 mins |