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  5. Invitrogen™ Rat 4-1BB/TNFRSF9/CD137 ELISA Kit

Invitrogen™ Rat 4-1BB/TNFRSF9/CD137 ELISA Kit

Catalog No. ERA1RBX5
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5 x 96 Tests
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ERA1RBX5 5 x 96 Tests
ERA1RB 96 Tests
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Description

ELISA

Rat 4-1BB/TNFRSF9/CD137 quantitates rat 4-1BB/TNFRSF9/CD137 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat 4-1BB/TNFRSF9/CD137.

CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival. Soluble forms of CD137 may provide negative control mechanism for some immune responses.

Specifications

Accession Number 4 1 BB; 41 BB; 4-1 BB; 4-1 BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; EGK
Assay Range 1.5 to 300 ng/mL
Assay Sensitivity 1.5 ng/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 500590
Gene Symbol TNFRSF9
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 5 x 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Storage Requirements 2°C to 8°C
Target 4-1 BB (CD137)
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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