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Invitrogen™ RAC2 Polyclonal Antibody
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Catalog No. PIPA5102362
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PIPA5102362 100 μL
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Catalog No. PIPA5102362 Supplier Invitrogen™ Supplier No. PA5102362
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RAC2.

RAC, a small GTPase in the ras family, regulates the formation of membrane ruffles, lamellipodia and filopodia. It is involved in cytoskeletal actin organization and transformation. The p21 activated kinases (PAKs) are direct targets of active Rac and Cdc42 which can induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts. RAC1 and RAC2 are also essential components of NADPH oxidase, the enzyme responsible for generating free radicals.

Specifications

Antigen RAC2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RAC2
Gene Accession No. P15153, Q05144
Gene Alias AI323801; AI452260; EN-7; EN-7 protein; Gx; HSPC022; p21-Rac2; Protein EN-7; RAC2; RAS-related C3 botulinum substrate 2; ras-related C3 botulinum toxin substrate 2; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2); Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2); small G protein
Gene Symbols RAC2
Host Species Rabbit
Immunogen A synthesized peptide derived from human RAC2(Accession P15153), corresponding to amino acid residues L160-L192.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19354, 366957, 5880
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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