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(R)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride, 98+%

CAS: 39637-99-5 | C10H8ClF3O2 | 252.62 g/mol

Supplier:  Thermo Scientific Chemicals L14325MF

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Catalog No. AAL14325MF


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Description

Description

(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride is used as a chiral acylating reagent, which is used in the resolution of amino acid enantiomers like 2,5-dimethoxy-4-methylamphetamine. It is also suitable for the determination of the optical composition of compounds extracted from biological fluids.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride is used as a chiral acylating reagent, which is used in the resolution of amino acid enantiomers like 2,5-dimethoxy-4-methylamphetamine. It is also suitable for the determination of the optical composition of compounds extracted from biological fluids.

Solubility
Sparingly miscible with water.

Notes
Moisture sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place.
Specifications

Specifications

(R)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride
1.353
89°C (192°F)
1.469
50 mg
3591565
14,6280
Sparingly miscible with water.
−137° (Neat)
(2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride
3080792
≥98%
39637-99-5
213°C to 214°C
C10H8ClF3O2
MFCD00044400
UN3265
Moisture sensitive
unii-81ut10uhv3, r---mtpa-cl, --alpha-methoxy-alpha-trifluoromethyl phenylacetyl chloride, r---alpha-methoxy-alpha-trifluoromethyl phenylacetyl chloride, r-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride, 2r-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride, r---a-methoxy-a-trifluoromethylphenylacetyl chloride, r---alpha-methoxy-alpha-trifluoromethylphenylacetyl chloride, --mtpa-cl, --mosher's acid chloride
PAORVUMOXXAMPL-VIFPVBQESA-N
CO[C@](C(Cl)=O)(C1=CC=CC=C1)C(F)(F)F
252.62
252.62

Chemical Identifiers

39637-99-5
252.62
PAORVUMOXXAMPL-VIFPVBQESA-N
3080792
CO[C@](C(Cl)=O)(C1=CC=CC=C1)C(F)(F)F
C10H8ClF3O2
MFCD00044400
unii-81ut10uhv3, r---mtpa-cl, --alpha-methoxy-alpha-trifluoromethyl phenylacetyl chloride, r---alpha-methoxy-alpha-trifluoromethyl phenylacetyl chloride, r-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride, 2r-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride, r---a-methoxy-a-trifluoromethylphenylacetyl chloride, r---alpha-methoxy-alpha-trifluoromethylphenylacetyl chloride, --mtpa-cl, --mosher's acid chloride
(2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride
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Safety and Handling

Safety and Handling

GHS H Statement
H314-H318-H227
Causes severe skin burns and eye damage.
Causes serious eye damage.
Combustible liquid.

P210-P235-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c

H227-H314-H335

DOTInformation : Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.

TSCA : No

Recommended Storage : Store at -20°C; Store under Nitrogen

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