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  6. Invitrogen™ QKI Recombinant Rabbit Monoclonal Antibody (23GB4595)

Invitrogen™ QKI Recombinant Rabbit Monoclonal Antibody (23GB4595)
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Catalog No. MA553776
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100 μL
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MA553776 100 μL
MA553777 20 μL
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Catalog No. MA553776 Supplier Invitrogen™ Supplier No. MA553776
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Description

Rabbit Recombinant Monoclonal Antibody

QKI Recombinant Monoclonal Antibody for Flow, ICC/IF, Western Blot

This gene encodes the sacsin protein, which includes a UbL domain at the N-terminus, a DnaJ domain, and a HEPN domain at the C-terminus. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. This gene includes a very large exon spanning more than 12.8 kb. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), a neurodegenerative disorder characterized by early-onset cerebellar ataxia with spasticity and peripheral neuropathy. Sacsin has been found to protect against mutant ataxin-1. A pseudogene associated with this gene is located on chromosome 11. Alternative splicing of this gene results in multiple transcript variants.

Specifications

Antigen QKI
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB4595
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene QKI
Gene Accession No. Q91XU1, Q96PU8, Q9QYS9
Gene Alias 1110003F05Rik; 1500005P18; DKFZp586I0923; HKQ; homolog of mouse quaking QKI (KH domain RNA binding protein); Hqk; hqkI; l(17)-1Wis; l17Wis1; lethal, Chr 17, U Wisconsin 1; MqkI; Protein quaking; protein quaking-like; Qk; QK1; QK3; Qka1; Qki; QKI, KH domain containing RNA binding; QKI, KH domain containing, RNA binding; QKI-5 protein; quaking; quaking homolog, KH domain RNA binding; RNA Binding (QKI); RNA binding protein HQK; rqkI
Gene Symbols Qk, QKI
Host Species Rabbit
Immunogen A synthesized peptide derived from QK1 (270-341AA).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100910212, 19317, 499022, 9444
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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