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Invitrogen™ PU.1 Monoclonal Antibody (E.388.3)

Description
It is not recommended to aliquot this antibody.
This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications
Specifications
| Antigen | PU.1 |
| Applications | ChIP Assay, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunoprecipitation, Western Blot |
| Classification | Monoclonal |
| Clone | E.388.3 |
| Concentration | 8 μg/mL |
| Conjugate | Unconjugated |
| Formulation | 0.01M HEPES with 50% glycerol, 0.15M NaCl, 100μg/mL BSA and <0.02% sodium azide; pH 7.5 |
| Gene | SPI1 |
| Gene Accession No. | P17433, P17947 |
| Gene Alias | 31 kDa transforming protein; 31 kDa-transforming protein; 31kDa Transforming Protein; Dis1; Dis-1; hCG_25181; hematopoietic transcription factor PU.1; OF; Pu.1; SFFV proviral integration 1; SFFV proviral integration 1 protein; Sfpi1; Sfpi-1; Spi1; SPI-1; Spi-1 proto-oncogene; SPIA; SPI-A; spleen focus forming virus (SFFV) proviral integration oncogene; spleen focus forming virus (SFFV) proviral integration oncogene spi1; spleen focus forming virus proviral integration oncogene spi1; Tcfpu1; Tfpu.1; Transcription factor PU.1; Transcription Factor spi1 |
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