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Invitrogen™ PSMD10 Polyclonal Antibody
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Catalog No. PIPA576644
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100 μL
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Catalog No. Quantity
PIPA576644 100 μL
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Catalog No. PIPA576644 Supplier Invitrogen™ Supplier No. PA576644
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.

Specifications

Antigen PSMD10
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene PSMD10
Gene Accession No. O75832, Q9Z2X2, Q9Z2X3
Gene Alias 26S proteasome non-ATPase regulatory subunit 10; 26S proteasome regulatory subunit p28; ankyrin repeat protein; AW554874; dJ889N15.2; Gankyrin; hepatocellular carcinoma-associated protein p28-II; p28; p28(GANK); p28Gank; proteasome (prosome, macropain) 26S subunit, non-ATPase, 10; proteasome 26S subunit, non-ATPase 10; proteasome subunit p28; proteosome (prosome, macropain) 26S subunit, non-ATPase, 10; proteosome subunit p28; PSMD10
Gene Symbols PSMD10
Host Species Rabbit
Immunogen Recombinant full length Human PSMD10.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116722, 53380, 5716
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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