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Invitrogen™ PSMB7 Monoclonal Antibody (OTI4G9)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA525900
Description
PSMB7 Monoclonal Antibody for Western Blot, ICC/IF
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit).Specifications
| PSMB7 | |
| Monoclonal | |
| 0.59 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P70195, Q99436, Q9JHW0 | |
| Psmb7 | |
| Human recombinant protein fragment corresponding to amino acids 58-277 of PSMB7 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat, Canine, Monkey | |
| Antibody | |
| IgG1 |
| Western Blot, Immunocytochemistry | |
| OTI4G9 | |
| Unconjugated | |
| Psmb7 | |
| AU020723; beta-type proteasome 7 subunit; EGK_07890; hypothetical protein LOC511207; macropain chain Z; MC14; Mmc14; Multicatalytic endopeptidase complex chain Z; proteasome (prosome, macropain) subunit, beta type 7; proteasome (prosome, macropain) subunit, beta type, 7; proteasome 20S subunit beta 7; proteasome beta 7 subunit; proteasome catalytic subunit 2; proteasome subunit alpha; proteasome subunit beta 7; proteasome subunit beta type-7; proteasome subunit beta type-7 proprotein; proteasome subunit Z; protein serine kinase c17; Psmb7; RP11-101K10.7; Z | |
| Mouse | |
| Affinity chromatography | |
| RUO | |
| 100686423, 19177, 5695, 85492 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |