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Invitrogen™ PRDX5 Monoclonal Antibody (K16265_10E10), Invitrogen™

Catalog No. MA556323
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200 μL
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MA556323 200 μL
MA555943 50 μL
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Catalog No. MA556323 Supplier Invitrogen™ Supplier No. MA556323
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Mouse Monoclonal Antibody

Sequence of this protein is as follows: MAPIKVGDAI PAVEVFEGEP GNKVNLAELF KGKKGVLFGV PGAFTPGCSK THLPGFVEQA EALKAKGVQV VACLSVNDAF VTGEWGRAHK AEGKVRLLAD PTGAFGKETD LLLDDSLVSI FGNRRLKRFS MVVQDGIVKA LNVEPDGTGL TCSLAPNIIS QL

Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.

Specifications

Antigen PRDX5
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone K16265_10E10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Gene PRDX5
Gene Accession No. P30044
Gene Alias ACR1; Alu corepressor 1; Alu co-repressor 1; Antioxidant enzyme B166; AOEB166; AOPP; B166; epididymis secretory protein Li 55; HEL-S-55; Liver tissue 2D-page spot 2D-0014IV; liver tissue 2D-page spot 71B; peroxiredoxin 5; peroxiredoxin 6; peroxiredoxin V; Peroxiredoxin-5, mitochondrial; peroxisomal antioxidant enzyme; peroxisomal membrane protein 20; PLP; Pmp20; PRDX5; Prdx6; Prx5; PrxV; prx-V; SBBI10; Thioredoxin peroxidase PMP20; thioredoxin reductase; TPx type VI
Gene Symbols PRDX5
Host Species Mouse
Immunogen Recombinant human PRDX5 (immunogen range is 53-214).
Purification Method Protein A
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25824
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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