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Invitrogen™ PRAK Monoclonal Antibody (7H10B4)
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Catalog No. PIMA515352
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100 μL
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Catalog No. Quantity
PIMA515352 100 μL
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Catalog No. PIMA515352 Supplier Invitrogen™ Supplier No. MA515352
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Description

Mouse Monoclonal Antibody

MA5-15352 targets PRAK in indirect ELISA, IHC and WB applications and shows reactivity with Human samples. The MA5-15352 immunogen is purified recombinant fragment of PRAK expressed in E. Coli.

MAPKAPK5 (PRAK) is activated in response to cellular stress and pro-inflammatory cytokines. Activity of this kinase is regulated by p38 alpha and p38 beta. The protein encoded by PRAK is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of PRAK encoding distinct isoforms have been reported.

Specifications

Antigen PRAK
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 7H10B4
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene MAPKAPK5
Gene Accession No. Q8IW41
Gene Alias MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; Mapkapk5; MAPKAP-K5; MAPKAPK-5; mitogen-activated protein kinase-activated protein kinase 5; MK5; MK-5; p38-regulated/activated protein kinase; PRAK
Gene Symbols MAPKAPK5
Host Species Mouse
Immunogen Purified recombinant fragment of PRAK expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8550
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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