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Invitrogen™ PMS1 Polyclonal Antibody

Description
Antibody detects endogenous levels of total PMS1.
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.
Specifications
Specifications
| Antigen | PMS1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | PMS1 |
| Gene Accession No. | P54277 |
| Gene Alias | DNA mismatch repair protein PMS1; HNPCC3; hPMS1; human homolog of yeast mutL; mismatch repair gene PMSL1; MLH2; PMS1; PMS1 homolog 1, mismatch repair system component; PMS1 postmeiotic segregation increased 1; PMS1 protein homolog 1; PMSL1; postmeiotic segregation increased 1 (S. cerevisiae); rhabdomyosarcoma antigen MU-RMS-40.10B; rhabdomyosarcoma antigen MU-RMS-40.10E |
| Gene Symbols | PMS1 |
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