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Invitrogen™ PKD2 Monoclonal Antibody (K49022_2E5), Invitrogen™

Catalog No. MA556070
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200 μL
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MA556070 200 μL
MA555690 50 μL
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Catalog No. MA556070 Supplier Invitrogen™ Supplier No. MA556070
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Mouse Monoclonal Antibody

Sequence of this protein is as follows: SDLIRKGYHK ALVKLKLKKN TVDDISESLR QGGGKLNFDE LRQDLKGKGH TDAEIEAIFT KYDQDGDQEL TEHEHQQMRD DLEKEREDLD LDHSSLPRPM SSRSFPRSLD DSEEDDDEDS GHSSRRRGSI SSGVSYEEFQ VLVRRVDRME HSIGSIVSKI DAVIVKLEIM ERAKLKRREV LGRLLDGVAE DERLGRDSEI HREQMERLVR EELERWESDD AASQISHGLG TPVGLNGQPR PRSSRPSSSQ

This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal dominant polycystic kidney disease.

Specifications

Antigen PKD2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone K49022_2E5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Gene PKD2
Gene Accession No. O35245, Q13563
Gene Alias A MGC138466; APKD2; Autosomal dominant polycystic kidney disease type II protein; C030034P18Rik; MGC138468; PC2; Pc-2; PKD2; PKD4; polycystic kidney disease 2; polycystic kidney disease 2 (autosomal dominant); polycystic kidney disease 2 homolog; Polycystic kidney disease 2 protein; Polycystic kidney disease 2 protein homolog; polycystin 2; polycystin 2, transient receptor potential cation channel; polycystin-2; Polycystwin; R48321; RGD1559992; transient receptor potential cation channel subfamily P member 2; transient receptor potential cation channel, subfamily P, member 2; TRPP1; TRPP2
Gene Symbols PKD2
Host Species Mouse
Immunogen Recombinant human PKD2 (immunogen range is 701-950).
Purification Method Protein A
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18764, 5311
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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