missing translation for 'onlineSavingsMsg'
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Invitrogen™ PKD2 Monoclonal Antibody (K49022_2E5), Invitrogen™
Description
Sequence of this protein is as follows: SDLIRKGYHK ALVKLKLKKN TVDDISESLR QGGGKLNFDE LRQDLKGKGH TDAEIEAIFT KYDQDGDQEL TEHEHQQMRD DLEKEREDLD LDHSSLPRPM SSRSFPRSLD DSEEDDDEDS GHSSRRRGSI SSGVSYEEFQ VLVRRVDRME HSIGSIVSKI DAVIVKLEIM ERAKLKRREV LGRLLDGVAE DERLGRDSEI HREQMERLVR EELERWESDD AASQISHGLG TPVGLNGQPR PRSSRPSSSQ
This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal dominant polycystic kidney disease.
Specifications
Specifications
| Antigen | PKD2 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Monoclonal |
| Clone | K49022_2E5 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| Gene | PKD2 |
| Gene Accession No. | O35245, Q13563 |
| Gene Alias | A MGC138466; APKD2; Autosomal dominant polycystic kidney disease type II protein; C030034P18Rik; MGC138468; PC2; Pc-2; PKD2; PKD4; polycystic kidney disease 2; polycystic kidney disease 2 (autosomal dominant); polycystic kidney disease 2 homolog; Polycystic kidney disease 2 protein; Polycystic kidney disease 2 protein homolog; polycystin 2; polycystin 2, transient receptor potential cation channel; polycystin-2; Polycystwin; R48321; RGD1559992; transient receptor potential cation channel subfamily P member 2; transient receptor potential cation channel, subfamily P, member 2; TRPP1; TRPP2 |
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