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Invitrogen™ PKC mu Recombinant Rabbit Monoclonal Antibody (23GB4590)

Description
PKC mu Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow
The PKC family of serine/threonine kinases, including PRKCN (PKD3), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent. PKC mu activation is dependent on the phosphorylation of two activation loop sites, Ser744 and Ser748, via a PKC-dependent signaling pathway.
Specifications
Specifications
| Antigen | PKC mu |
| Applications | Flow Cytometry, Western Blot, Immunocytochemistry |
| Classification | Recombinant Monoclonal |
| Clone | 23GB4590 |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | Prkd3 |
| Gene Accession No. | O94806, Q15139, Q5XIS9, Q62101, Q8BZ03, Q8K1Y2, Q9BZL6, Q9WTQ1 |
| Gene Alias | 4930557O20Rik; 5730497N19Rik; AI325941; DKFZP586E0820; EPK2; HSPC187; nPKC-D1; nPKC-D2; nPKC-mu; nPKC-nu; PKC mu; PKC nu; PKC u; PKC v; Pkcm; PKCmu; PKC-MU; Pkcnu; PKC-NU; PKCu; PKC-u; PKCv; PKC-v; Pkd; PKD1; PKD2; PKD3; Prkcm; PRKCN; Prkd1; PRKD2; PRKD3; Protein kinase C mu type; protein kinase C nu type; protein kinase C, mu; protein kinase C, nu; protein kinase D; protein kinase D1; protein kinase D2; protein kinase D3; protein kinase EPK2; RGD1308054; Serine/threonine-protein kinase D1; serine/threonine-protein kinase D2; Serine/threonine-protein kinase D3 |
| Gene Symbols | PRKD1, Prkd2, Prkd3 |
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