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Invitrogen™ Pirh2 Recombinant Rabbit Monoclonal Antibody (4Q5H9)
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Catalog No. PIMA537910
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100 μL
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PIMA537910 100 μL
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Catalog No. PIMA537910 Supplier Invitrogen™ Supplier No. MA537910
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Rabbit Recombinant Monoclonal Antibody

Positive Samples: HCT116 Immunogen sequence: HVLPCGHLLH RTCYEEMLKE GYRCPLCMHS ALDMTRYWRQ LDDEVAQTPM PSEYQNMTVD ILCNDCNGRS TVQFHILGMK CKICESYNTA QAGGRRISLD QQ.

The protein encoded by this gene has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

Antigen Pirh2
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 4Q5H9
Concentration 1.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RCHY1
Gene Accession No. Q96PM5, Q9CR50
Gene Alias Androgen receptor N-terminal-interacting protein; androgen-receptor N-terminal-interacting protein; ARNIP; Chimp; CH-rich interacting match with PLAG1; CH-rich-interacting match with PLAG1; DKFZp586C1620; E3 ubiquitin-protein ligase Pirh2; h PRO1996; hPirh2; p53-induced protein with a RING-H2 domain; p53-induced RING-H2 protein; PIRH2; PIRH2E; PIRH2F; PRO1996; RCHY1; ring finger and CHY zinc finger domain containing 1; ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase; RING finger and CHY zinc finger domain-containing protein 1; RING finger protein 199; RING-type E3 ubiquitin transferase RCHY1; RNF199; ZCHY; Zfp363; Zinc finger protein 363; zinc finger, CHY-type; Znf363
Gene Symbols RCHY1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 160-261 of human RCHY1 (Q96PM5).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25898, 68098
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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