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Invitrogen™ Phospho-TrkA/TrkB (Tyr674, Tyr675, Tyr706, Tyr707) Monoclonal Antibody (C.795.3)
Rabbit Monoclonal Antibody
Supplier: Invitrogen™ MA514927
Description
It is not recommended to aliquot this antibody.
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.Chemical Identifiers
| Phospho-TrkA/TrkB (Tyr674, Tyr675, Tyr706, Tyr707) | |
| 36 μg/mL | |
| Immunoprecipitation, Western Blot | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5 | |
| P04629, P35739, Q16620, Q63604 | |
| 25054, 4914, 4915, 59109 | |
| Synthetic phosphopeptide corresponding to residues surrounding pTyr674/675 of human TrkA. | |
| Antibody |
| C.795.3 | |
| -20°C | |
| Monoclonal | |
| Liquid | |
| IgG | |
| Human, Rat, Rat | |
| NTRK1 | |
| BDNF/NT-3 growth factors receptor; BDNF-tropomyosine receptor kinase B; C80751; gp140trk; GP145-TrkB; GP145-TrkB/GP95-TrkB; high affinity nerve growth factor receptor; MTC; neural receptor protein-tyrosine kinase (trkB); neurotrophic receptor tyrosine kinase 1; neurotrophic receptor tyrosine kinase 2; Neurotrophic tyrosine kinase receptor type 1; Neurotrophic tyrosine kinase receptor type 2; neurotrophic tyrosine kinase, receptor, type 1; neurotrophic tyrosine kinase, receptor, type 2; neurotrophic tyrosine receptor kinase type 2; NTRK1; NTRK2; Oncogene TRK; p140-TrkA; RATTRKB1; Slow nerve growth factor receptor; Tkr; Tkrb; trk; TRK1; TRK1-transforming tyrosine kinase protein; Trka; trk-A; TrkA neurotrophin receptor; trkA proto-oncogene receptor; TRKB; Trk-B; TrkB tyrosine kinase; TRKB1; Tropomyosin-related kinase A; tropomyosin-related kinase B; Tyrosine kinase receptor; Tyrosine kinase receptor A; tyrosine kinase receptor B | |
| NTRK1, Ntrk2 | |
| Primary | |
| Affinity chromatography |
Specifications
| Phospho-TrkA/TrkB (Tyr674, Tyr675, Tyr706, Tyr707) | |
| Monoclonal | |
| 36 μg/mL | |
| 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5 | |
| P04629, P35739, Q16620, Q63604 | |
| NTRK1, Ntrk2 | |
| Synthetic phosphopeptide corresponding to residues surrounding pTyr674/675 of human TrkA. | |
| 100 μL | |
| Primary | |
| Human, Rat, Rat | |
| Antibody | |
| IgG |
| Immunoprecipitation, Western Blot | |
| C.795.3 | |
| Unconjugated | |
| NTRK1 | |
| BDNF/NT-3 growth factors receptor; BDNF-tropomyosine receptor kinase B; C80751; gp140trk; GP145-TrkB; GP145-TrkB/GP95-TrkB; high affinity nerve growth factor receptor; MTC; neural receptor protein-tyrosine kinase (trkB); neurotrophic receptor tyrosine kinase 1; neurotrophic receptor tyrosine kinase 2; Neurotrophic tyrosine kinase receptor type 1; Neurotrophic tyrosine kinase receptor type 2; neurotrophic tyrosine kinase, receptor, type 1; neurotrophic tyrosine kinase, receptor, type 2; neurotrophic tyrosine receptor kinase type 2; NTRK1; NTRK2; Oncogene TRK; p140-TrkA; RATTRKB1; Slow nerve growth factor receptor; Tkr; Tkrb; trk; TRK1; TRK1-transforming tyrosine kinase protein; Trka; trk-A; TrkA neurotrophin receptor; trkA proto-oncogene receptor; TRKB; Trk-B; TrkB tyrosine kinase; TRKB1; Tropomyosin-related kinase A; tropomyosin-related kinase B; Tyrosine kinase receptor; Tyrosine kinase receptor A; tyrosine kinase receptor B | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 25054, 4914, 4915, 59109 | |
| -20°C | |
| Liquid |