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Invitrogen™ Phospho-TFEB (Ser211) Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5114662
Description
Antibody detects endogenous levels of TFEB only when phosphorylated at Ser211.
The Transcription factor EB (TFEB) is a member in the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors. Recent studies have shown that lysosomal biogenesis is regulated by TFEB, which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1. Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes.Specifications
| Phospho-TFEB (Ser211) | |
| Polyclonal | |
| Unconjugated | |
| TFEB | |
| Alpha TCFEB; ALPHATFEB; BHLHE35; Class E basic helix-loop-helix protein 35; RP4-696P19.3; T-cell transcription factor EB; Tcfeb; Tfeb; Transcription factor EB | |
| Rabbit | |
| Sequential chromatography | |
| RUO | |
| 21425, 316214, 7942 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P19484, Q9R210 | |
| TFEB | |
| A synthesized peptide derived from human TFEB around the phosphorylation site of Ser211. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |