missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ Phospho-SHP2 (Tyr542) Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ 44554G
Description
Phospho-SHP2 (Tyr542) Polyclonal Antibody for ICC/IF, IHC (P), Western Blot
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.Chemical Identifiers
| Phospho-SHP2 (Tyr542) | |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3 | |
| P35235, Q06124 | |
| 19247, 5781 | |
| The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human SHP2 that contains tyrosine 542. The sequence is conserved in mouse, rat and chicken. | |
| Antibody |
| -20°C | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human, Mouse | |
| PTPN11 | |
| 2700084A17Rik; AW536184; bptp3; CFC; cSH-PTP2; encodes catalytic domain; HCP; HGNC:9644; JMML; METCDS; MGC14433; Noonan syndrome 1; ns1; null; OTTHUMP00000166108; phosphotyrosyl-protein phosphatase; protein tyrosine phosphatase non-receptor type 11; protein tyrosine phosphatase SH-PTP2; protein tyrosine phosphatase, non-receptor type 11; protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1); protein tyrosine phosphatase, non-receptor type 11 S homeolog; protein-tyrosine phosphatase 1D; Protein-tyrosine phosphatase 2C; protein-tyrosine phosphatase SYP; PTP1C; PTP1D; PTP-1D; ptp-2; PTP2C; PTP-2C; Ptpn11; ptpn11.S; ptpn11-a; ptpn11-b; SAP-2; SH2 domain-containing protein tyrosine phosphatase-2; Shp2; shp-2; SHPTP2; SH-PTP2; SH-PTP2 protein tyrosine phosphatase non-receptor type 11; SH-PTP2 protein tyrosine phosphatase, non-receptor type 11; SH-PTP3; Syp; Tyrosine-protein phosphatase non-receptor type 11; XELAEV_18010676mg | |
| PTPN11 | |
| Primary | |
| Antigen affinity chromatography |
Specifications
| Phospho-SHP2 (Tyr542) | |
| Polyclonal | |
| Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3 | |
| P35235, Q06124 | |
| PTPN11 | |
| The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human SHP2 that contains tyrosine 542. The sequence is conserved in mouse, rat and chicken. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| Unconjugated | |
| PTPN11 | |
| 2700084A17Rik; AW536184; bptp3; CFC; cSH-PTP2; encodes catalytic domain; HCP; HGNC:9644; JMML; METCDS; MGC14433; Noonan syndrome 1; ns1; null; OTTHUMP00000166108; phosphotyrosyl-protein phosphatase; protein tyrosine phosphatase non-receptor type 11; protein tyrosine phosphatase SH-PTP2; protein tyrosine phosphatase, non-receptor type 11; protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1); protein tyrosine phosphatase, non-receptor type 11 S homeolog; protein-tyrosine phosphatase 1D; Protein-tyrosine phosphatase 2C; protein-tyrosine phosphatase SYP; PTP1C; PTP1D; PTP-1D; ptp-2; PTP2C; PTP-2C; Ptpn11; ptpn11.S; ptpn11-a; ptpn11-b; SAP-2; SH2 domain-containing protein tyrosine phosphatase-2; Shp2; shp-2; SHPTP2; SH-PTP2; SH-PTP2 protein tyrosine phosphatase non-receptor type 11; SH-PTP2 protein tyrosine phosphatase, non-receptor type 11; SH-PTP3; Syp; Tyrosine-protein phosphatase non-receptor type 11; XELAEV_18010676mg | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 19247, 5781 | |
| -20°C | |
| Liquid |