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Invitrogen™ Phospho-PRAK (Thr182) Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA599148
Description
Antibody detects endogenous levels of MAPKAPK5 only when phosphorylated at Threonine 182.
MAPKAPK5 (PRAK) is activated in response to cellular stress and pro-inflammatory cytokines. Activity of this kinase is regulated by p38 alpha and p38 beta. The protein encoded by PRAK is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of PRAK encoding distinct isoforms have been reported.Chemical Identifiers
| Phospho-PRAK (Thr182) | |
| -20°C | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human, Mouse | |
| MAPKAPK5 | |
| MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; Mapkapk5; MAPKAP-K5; MAPKAPK-5; mitogen-activated protein kinase-activated protein kinase 5; MK5; MK-5; p38-regulated/activated protein kinase; PRAK | |
| MAPKAPK5 | |
| Primary | |
| Sequential chromatography |
| 1 mg/mL | |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O54992, Q8IW41 | |
| 17165, 8550 | |
| A synthesized peptide derived from human MAPKAPK5(Accession Q8IW41), corresponding to amino acid residues around phosphorylated Thr182. | |
| Antibody |
Specifications
| Phospho-PRAK (Thr182) | |
| Polyclonal | |
| Unconjugated | |
| MAPKAPK5 | |
| MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; Mapkapk5; MAPKAP-K5; MAPKAPK-5; mitogen-activated protein kinase-activated protein kinase 5; MK5; MK-5; p38-regulated/activated protein kinase; PRAK | |
| Rabbit | |
| Sequential chromatography | |
| RUO | |
| 17165, 8550 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O54992, Q8IW41 | |
| MAPKAPK5 | |
| A synthesized peptide derived from human MAPKAPK5(Accession Q8IW41), corresponding to amino acid residues around phosphorylated Thr182. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |