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Invitrogen™ Phospho-MARCKS (Ser170) Polyclonal Antibody
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Catalog No. PIPA5105558
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100 μL
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PIPA5105558 100 μL
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Catalog No. PIPA5105558 Supplier Invitrogen™ Supplier No. PA5105558
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of MARCKS only when phosphorylated at Ser170.

MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

Specifications

Antigen Phospho-MARCKS (Ser170)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MARCKS
Gene Accession No. P26645, P29966, P30009
Gene Alias 80K protein; 80K-L; 80K-L protein; FLJ14368; FLJ90045; KINC; Macs; MARCKS; MARCS; myristoylated alanine rich protein kinase C substrate; myristoylated alanine-rich C-kinase substrate; Myristoylated alanine-rich protein kinase C substrate; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); phosphomyristin; PKCSL; PRKCSL; protein kinase C substrate 80 kDa protein; protein kinase C substrate, 80 kDa protein, light chain
Gene Symbols MARCKS
Host Species Rabbit
Immunogen A synthesized peptide derived from human MARCKS(Accession P29966), corresponding to amino acid residues around phosphorylated Ser170.
Purification Method sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17118, 25603, 4082
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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