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Invitrogen™ Phospho-ERK3 (Ser189) Polyclonal Antibody
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Catalog No. PIPA5105666
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100 μL
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Catalog No. Quantity
PIPA5105666 100 μL
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Catalog No. PIPA5105666 Supplier Invitrogen™ Supplier No. PA5105666
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of MAPK6/ERK3 only when phosphorylated at Ser189.

The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. Tissue specificity: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.

Specifications

Antigen Phospho-ERK3 (Ser189)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MAPK6
Gene Accession No. P27704, Q16659, Q61532
Gene Alias 2610021I23Rik; D130053K17Rik; DKFZp686F03189; erk3; ERK-3; Erk-3 related; Extracellular signal-regulated kinase 3; extracellular signal-regulated kinase, p97; HsT17250; LOC538094 protein; MAP kinase 6; MAP kinase isoform p97; MAPK 6; Mapk4; Mapk6; Mapk63; mitogen activated protein kinase 4; mitogen activated protein kinase 6; mitogen-activated protein kinase 6; p55-MAPK; p97mapk; p97-MAPK; Prkm4; Prkm6; protein kinase, mitogen activated kinase 4; protein kinase, mitogen-activated 5; protein kinase, mitogen-activated 6; si:ch211-235f12.1
Gene Symbols MAPK6
Host Species Rabbit
Immunogen A synthesized peptide derived from human MAPK6(Accession Q16659), corresponding to amino acid residues around phosphorylated Ser189.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 50772, 5597, 58840
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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