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Invitrogen™ Phospho-CAD (Ser1859) Polyclonal Antibody
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Catalog No. PIPA5105158
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100 μL
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PIPA5105158 100 μL
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Catalog No. PIPA5105158 Supplier Invitrogen™ Supplier No. PA5105158
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of CAD only when phosphorylated at Ser1859.

The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.

Specifications

Antigen Phospho-CAD (Ser1859)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CAD
Gene Accession No. B2RQC6, P27708
Gene Alias 2410008J01Rik; 38E.19; anon-WO2004063362.83; Aspartate carbamoyltransferase; AU018859; cad; CAD protein; CAD trifunctional protein; cad-PA; cad-PB; cad-PC; carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; carbamoylphosphate synthetase 2/aspartate transcarbamylase/dihydroorotase; carbamyl phosphatate synthetase 2; caudal; cb456; cd; CDG1Z; CG1759; CG1759-PA; CG1759-PB; CG1759-PC; Cpad; Dihydroorotase; Dmel\CG1759; Dmel_CG1759; Glutamine-dependent carbamoyl-phosphate synthase; Homeotic protein caudal; LD29596p; multifunctional protein CAD; S67; si:dkey-221h15.3; wu:fc30c12; wu:fc33d01; wu:fc67g02
Gene Symbols CAD
Host Species Rabbit
Immunogen A synthesized peptide derived from human CAD(Accession P27708), corresponding to amino acid residues around phosphorylated Ser1859.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24240, 69719, 790
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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