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Invitrogen™ Phospho-AMPK alpha-1 (Ser486) Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA536615
Description
This antibody detects endogenous protein at a molecular weight of 63 kDa. It does not cross-react with phosphorylated AMPK alpha-2 or other related proteins. Purity is >95% by SDS-PAGE.
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.Chemical Identifiers
| Phospho-AMPK alpha-1 (Ser486) | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human, Mouse, Rat | |
| Prkaa1 | |
| 5'-AMP-activated protein kinase alpha-1 catalytic subunit; 5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase, catalytic alpha-1 chain; 63 kDa subunit; AAPK2; ACACA kinase; Acetyl-CoA carboxylase kinase; activated protein kinase; AI194361; AI450832; AL024255; AMP -activate kinase alpha 1 subunit; AMP activated protein kinase; AMP-activated protein kinase, alpha 1 catalytic subunit; AMP-activated protein kinase, catalytic, alpha-1; AMPK; AMPK 63 kDa subunit; AMPK alpha 1; AMPK alpha-1 chain; AMPK subunit alpha-1; AMPK subunit pAMPK; AMPK1; AMPK2; AMPKa1; AMPKalpha1; AMPK-alpha-2 chain; C130083N04Rik; HMGCR kinase; hydroxymethylglutaryl-CoA reductase kinase; MGC33776; MGC57364; pAMPK; PRKAA; Prkaa1; PRKAA2; protein kinase; protein kinase AMP-activated catalytic subunit alpha 1; protein kinase, AMP-activated, alpha 1 catalytic subunit; tau-protein kinase PRKAA1 | |
| Prkaa1 | |
| Primary | |
| Antigen affinity chromatography |
| 1 mg/mL | |
| Immunohistochemistry (Paraffin), Western Blot | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
| P54645, Q13131, Q5EG47 | |
| 105787, 5562, 65248 | |
| Synthetic phosphopeptide derived from human AMPK alpha1 around the phosphorylation site of Serine 486. | |
| Antibody |
Specifications
| Phospho-AMPK alpha-1 (Ser486) | |
| Polyclonal | |
| Unconjugated | |
| Prkaa1 | |
| 5'-AMP-activated protein kinase alpha-1 catalytic subunit; 5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase, catalytic alpha-1 chain; 63 kDa subunit; AAPK2; ACACA kinase; Acetyl-CoA carboxylase kinase; activated protein kinase; AI194361; AI450832; AL024255; AMP -activate kinase alpha 1 subunit; AMP activated protein kinase; AMP-activated protein kinase, alpha 1 catalytic subunit; AMP-activated protein kinase, catalytic, alpha-1; AMPK; AMPK 63 kDa subunit; AMPK alpha 1; AMPK alpha-1 chain; AMPK subunit alpha-1; AMPK subunit pAMPK; AMPK1; AMPK2; AMPKa1; AMPKalpha1; AMPK-alpha-2 chain; C130083N04Rik; HMGCR kinase; hydroxymethylglutaryl-CoA reductase kinase; MGC33776; MGC57364; pAMPK; PRKAA; Prkaa1; PRKAA2; protein kinase; protein kinase AMP-activated catalytic subunit alpha 1; protein kinase, AMP-activated, alpha 1 catalytic subunit; tau-protein kinase PRKAA1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 105787, 5562, 65248 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
| P54645, Q13131, Q5EG47 | |
| Prkaa1 | |
| Synthetic phosphopeptide derived from human AMPK alpha1 around the phosphorylation site of Serine 486. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |