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Invitrogen™ Phospho-4EBP1/2/3 (Thr46, Thr32) Recombinant Rabbit Monoclonal Antibody (23GB3850)
Description
Phospho-4EBP1/2/3 (Thr46, Thr32) Recombinant Monoclonal Antibody for Flow, ICC/IF, Western Blot
4EBP1, 4EBP2, and 4EBP3 are members of the eukaryotic translation initiation factor 4E-binding protein (4EBP) family. These proteins play a crucial role in the regulation of protein synthesis, specifically by controlling the availability of the eukaryotic translation initiation factor 4E (eIF4E). 4EBP1, 4EBP2, and 4EBP3 are structurally similar but exhibit some differences in their tissue distribution and expression levels. They are widely expressed in various tissues and cell types and have been implicated in the regulation of different biological processes, including cell growth, proliferation, and survival. Dysregulation of 4EBP proteins has also been associated with various diseases, including cancer.
Specifications
Specifications
| Antigen | Phospho-4EBP1/2/3 (Thr46, Thr32) |
| Applications | Flow Cytometry, Western Blot, Immunocytochemistry |
| Classification | Recombinant Monoclonal |
| Clone | 23GB3850 |
| Concentration | 0.4 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | EIF4EBP1 |
| Gene Accession No. | Q13541, Q60876, Q62622 |
| Gene Alias | 4EBP1/2/3; 4E-BP1/2/3; BP-1/2/3; EIF4E-Binding Protein 1/2/3; EIF4EBP1/2/3; Eukaryotic Translation Initiation Factor 4E Binding Protein 1/2/3; Eukaryotic Translation Initiation Factor 4E-Binding Protein 1/2/3; PHAS-I; Phosphorylated Heat- And Acid-Stable Protein Regulated By Insulin 1/2/3 |
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