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Phenyl phosphorodichloridate, 97%, Thermo Scientific Chemicals

$56.78 - $575.25

Chemical Identifiers

CAS 770-12-7
Molecular Formula C6H5Cl2O2P
Molecular Weight (g/mol) 210.978
MDL Number MFCD00002067
InChI Key TXFOLHZMICYNRM-UHFFFAOYSA-N
Synonym phenyl dichlorophosphate, phenyl phosphorodichloridate, dichlorophenoxyphosphine oxide, phosphorodichloridic acid, phenyl ester, phenylphosphoric dichloride, phenyl phosphorodichlorodate, phenoxydichlorophosphine oxide, phenyldichlorophosphate, phenoxyphosphoryl dichloride, phosphoroyl dichloride phenyl ester
PubChem CID 13038
IUPAC Name dichlorophosphoryloxybenzene
SMILES C1=CC=C(C=C1)OP(=O)(Cl)Cl
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Products 3
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAA1047914
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Thermo Scientific Chemicals
A1047914
25 g
Each for $56.78
 
AAA1047922
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Thermo Scientific Chemicals
A1047922
100 g
Each for $126.00
 
AAA1047936
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Thermo Scientific Chemicals
A1047936
500 g
Each for $575.25
 
Description

Description

Reagent for preparation of phosphate diesters.Phenyl phosphorodichloridate is used in the preparation of symmetrical phosphate diesters. It is used as a phosphorylating agent for alcohols and amines. It is also involved in the preparation of phenylphosphoro di-(1-imidazolidate) and 2-phenyl-bis-triazoloylphosphate, which is used in peptide synthesis. It plays a vital role in the Pfitzner-Moffatt oxidation which involves oxidation of alcohols to the corresponding aldehydes and ketones. Furthermore, it is utilized in Beckmann rearrangement for the preparation of N-phenylacetamide from acetophenone oxime.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Reagent for preparation of phosphate diesters.Phenyl phosphorodichloridate is used in the preparation of symmetrical phosphate diesters. It is used as a phosphorylating agent for alcohols and amines. It is also involved in the preparation of phenylphosphoro di-(1-imidazolidate) and 2-phenyl-bis-triazoloylphosphate, which is used in peptide synthesis. It plays a vital role in the Pfitzner-Moffatt oxidation which involves oxidation of alcohols to the corresponding aldehydes and ketones. Furthermore, it is utilized in Beckmann rearrangement for the preparation of N-phenylacetamide from acetophenone oxime.

Solubility
Immiscible with water.

Notes
Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong bases, alcohols and strong oxidizing agents.
Specifications

Chemical Identifiers

770-12-7
210.978
TXFOLHZMICYNRM-UHFFFAOYSA-N
13038
C1=CC=C(C=C1)OP(=O)(Cl)Cl
C6H5Cl2O2P
MFCD00002067
phenyl dichlorophosphate, phenyl phosphorodichloridate, dichlorophenoxyphosphine oxide, phosphorodichloridic acid, phenyl ester, phenylphosphoric dichloride, phenyl phosphorodichlorodate, phenoxydichlorophosphine oxide, phenyldichlorophosphate, phenoxyphosphoryl dichloride, phosphoroyl dichloride phenyl ester
dichlorophosphoryloxybenzene

Specifications

770-12-7
1.415
112°C (233°F)
1.523
25 g
511863
phenyl dichlorophosphate, phenyl phosphorodichloridate, dichlorophenoxyphosphine oxide, phosphorodichloridic acid, phenyl ester, phenylphosphoric dichloride, phenyl phosphorodichlorodate, phenoxydichlorophosphine oxide, phenyldichlorophosphate, phenoxyphosphoryl dichloride, phosphoroyl dichloride phenyl ester
TXFOLHZMICYNRM-UHFFFAOYSA-N
dichlorophosphoryloxybenzene
13038
97%
-1°C
241°C to 243°C
C6H5Cl2O2P
MFCD00002067
UN3265
Moisture sensitive
Immiscible with water.
C1=CC=C(C=C1)OP(=O)(Cl)Cl
210.978
210.98
Phenyl phosphorodichloridate
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Safety and Handling

Safety and Handling

GHS H Statement
H314-H318-H302
Causes severe skin burns and eye damage.
Causes serious eye damage.
Harmful if swallowed.

P260-P264b-P270-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c

H302-H314

DOTInformation : Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.

EINECSNumber : 212-220-6

RTECSNumber : TD4393000

TSCA : Yes

Recommended Storage : Ambient temperatures; Store under Nitrogen

SDS
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RUO – Research Use Only