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Invitrogen™ PHC3 Polyclonal Antibody

Description
Immunogen sequence: GVLSSSQNGP PKSTSQTQSL TICHNKTTVT SSKISQRDPS PESNKKGESP SLESRSTAVT RTSSIHQLIA PASYSPIQPH SLIKHQQIPL HSPPSKVSHH Q Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 94%.
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Specifications
Specifications
| Antigen | PHC3 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | PHC3 |
| Gene Accession No. | Q8NDX5 |
| Gene Alias | E030046K01Rik; early development regulator 3; early development regulatory protein 3; EDR3; homolog of polyhomeotic 3; hPH3; PH3; Phc3; polyhomeotic 3; polyhomeotic homolog 3; polyhomeotic homolog 3 (Drosophila); polyhomeotic like 3; polyhomeotic-like 3 (Drosophila); polyhomeotic-like protein 3 |
| Gene Symbols | PHC3 |
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