missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Pentafluorobenzene, 98+%
CAS: 363-72-4 | C6HF5 | 168.07 g/mol
Supplier: Thermo Scientific Chemicals A1394822
Description
Pentafluorobenzene is a fluorinated benzene with anesthetic properties. Pentafluorobenzene has been shown to potently and reversibly inhibited human α4β2 neuronal nicotinic acetylcholine receptor depe ndent on drug hydrophobicity in Xenopus laevis oocyte. New reaction conditions are described that enable the direct arylation of pentafluorobenzene with sterically encumbered aryl bromides and aryl chlorides. Bis (pentafluoropheny1) methane and tris (pentafluoropheny1) methane were prepared in 77 and 92% yields, respectively, by a Friedel-Crafts reaction of pentafluorobenzene with methylene chloride and chloroform using aluminum chloride as the Lewis acid.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsPentafluorobenzene is a fluorinated benzene with anesthetic properties. Pentafluorobenzene has been shown to potently and reversibly inhibited human α4β2 neuronal nicotinic acetylcholine receptor depe ndent on drug hydrophobicity in Xenopus laevis oocyte. New reaction conditions are described that enable the direct arylation of pentafluorobenzene with sterically encumbered aryl bromides and aryl chlorides. Bis (pentafluoropheny1) methane and tris (pentafluoropheny1) methane were prepared in 77 and 92% yields, respectively, by a Friedel-Crafts reaction of pentafluorobenzene with methylene chloride and chloroform using aluminum chloride as the Lewis acid.
Solubility
Insoluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
Specifications
| Pentafluorobenzene | |
| -48°C | |
| 84°C to 85°C | |
| C6HF5 | |
| MFCD00000286 | |
| UN1993 | |
| pentafluorobenzene, benzene, pentafluoro, unii-ih36lu53xs, benzene, 1,2,3,4,5-pentafluoro, 2,3,4,5,6-pentafluorobenzene, ih36lu53xs, 1,2,3,4,5-pentafluoro-benzene, pentafluorophenyl, benzenepentafluoride, pubchem2310 | |
| WACNXHCZHTVBJM-UHFFFAOYSA-N | |
| 1,2,3,4,5-pentafluorobenzene | |
| 9696 | |
| ≥98% |
| 363-72-4 | |
| 1.518 | |
| 13°C (55°F) | |
| 1.391 | |
| 100 g | |
| 1911549 | |
| Insoluble in water. | |
| FC1=CC(F)=C(F)C(F)=C1F | |
| 168.07 | |
| 168.06 |
Chemical Identifiers
| 363-72-4 | |
| 168.07 | |
| WACNXHCZHTVBJM-UHFFFAOYSA-N | |
| 9696 | |
| FC1=CC(F)=C(F)C(F)=C1F |
| C6HF5 | |
| MFCD00000286 | |
| pentafluorobenzene, benzene, pentafluoro, unii-ih36lu53xs, benzene, 1,2,3,4,5-pentafluoro, 2,3,4,5,6-pentafluorobenzene, ih36lu53xs, 1,2,3,4,5-pentafluoro-benzene, pentafluorophenyl, benzenepentafluoride, pubchem2310 | |
| 1,2,3,4,5-pentafluorobenzene |
Safety and Handling
GHS H Statement
H225-H302
Highly flammable liquid and vapour.
Harmful if swallowed.
P210-P233-P235-P240-P241-P242-P243-P261-P264b-P270-P271-P280-P301+P312-P303+P361+P353-P304+P340-P305+P351+P338-P312-P330-P332+P313-P363-P370+P378q-P501c
H225-H302-H315-H319-H335
DOTInformation : Hazard Class: 3; Packaging Group: II
EINECSNumber : 206-658-7
RTECSNumber : DA6651600
TSCA : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only