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Invitrogen™ PARL Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA520579
Description
Despite its predicted molecular weight of ~42kDa, PARL is observed at a higher molecular weight in SDS-PAGE. A suggested positive control is NIH-3T3 cell lysate. PA5-20579 can be used with blocking peptide PEP-0699.
This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.Chemical Identifiers
| PARL | |
| 4°C | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human, Mouse, Rat | |
| PARL | |
| D16Ertd607e; Mitochondrial intramembrane cleaving protease PARL; mitochondrial intramembrane-cleaving protease PARL; Parl; parl {ECO:0000250; Pbeta; P-beta; presenilin associated rhomboid like; presenilin associated, rhomboid-like; presenilin associated, rhomboid-like isoform 1 preproprotein; presenilin associated, rhomboid-like preproprotein; presenilins-associated rhomboid-like protein, mitochondrial; PRO2207; Psarl; PSARL1; PSENIP2; RHBDS1; rhomboid 7 homolog 1; UniProtKB:Q9H300} | |
| PARL | |
| Primary | |
| Antigen affinity chromatography |
| 1 mg/mL | |
| Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 0.02% sodium azide | |
| Q3B8P0, Q5XJY4, Q9H300 | |
| 287979, 381038, 55486 | |
| A 15 amino acid peptide from near the amino terminus of human PARL. | |
| Antibody |
Specifications
| PARL | |
| Polyclonal | |
| Unconjugated | |
| PARL | |
| D16Ertd607e; Mitochondrial intramembrane cleaving protease PARL; mitochondrial intramembrane-cleaving protease PARL; Parl; parl {ECO:0000250; Pbeta; P-beta; presenilin associated rhomboid like; presenilin associated, rhomboid-like; presenilin associated, rhomboid-like isoform 1 preproprotein; presenilin associated, rhomboid-like preproprotein; presenilins-associated rhomboid-like protein, mitochondrial; PRO2207; Psarl; PSARL1; PSENIP2; RHBDS1; rhomboid 7 homolog 1; UniProtKB:Q9H300} | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 287979, 381038, 55486 | |
| 4°C | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| Q3B8P0, Q5XJY4, Q9H300 | |
| PARL | |
| A 15 amino acid peptide from near the amino terminus of human PARL. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |